1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-132931
    TCMDC-125457
    Modulator
    TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
    TCMDC-125457
  • HY-N0716BR
    Berberine sulfate (Standard)
    Berberine (sulfate) (Standard) is the analytical standard of Berberine (sulfate). This product is intended for research and analytical applications. Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability[1][2].
    Berberine sulfate (Standard)
  • HY-17594R
    Oxyclozanide (Standard)
    Inhibitor
    Oxyclozanide (Standard) is the analytical standard of Oxyclozanide. This product is intended for research and analytical applications. Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity.
    Oxyclozanide (Standard)
  • HY-126640
    Phomoxanthone A
    Inhibitor
    Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively.
    Phomoxanthone A
  • HY-151148
    Trypanothione synthetase-IN-1
    Trypanothione synthetase-IN-1 (Compound 1) is a competitive Leishmania infantum trypanothione synthetase (TryS) inhibitor with an IC50 of 14.8 μM when triamine spermidine is as polyamine S.
    Trypanothione synthetase-IN-1
  • HY-155399
    Antitrypanosomal agent 16
    Antitrypanosomal agent 16 is a trypanocide with IC50 of 0.04μM in T. congolense strain IL3000.
    Antitrypanosomal agent 16
  • HY-123601
    DHQZ 36
    Inhibitor
    DHQZ 36 is a potent inhibitor of retrograde trafficking. DHQZ 36 inhibits Leishmania amazonensis infection in macrophages with an EC50 of 13.63 μM. DHQZ 36 has potent anti-parasite activity.
    DHQZ 36
  • HY-N0193S
    Artesunate-d3
    Inhibitor
    Artesunate-d3 is the deuterium labeled Artesunate. Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).
    Artesunate-d<sub>3</sub>
  • HY-169507
    Anthelvencin A
    Inhibitor
    Anthelvencin A is a pyrrolamide metabolite with moderate antibacterial and anthelmintic activities.
    Anthelvencin A
  • HY-113542
    Blasticidin A
    Blasticidin A ((+)-Blasticidin A) is an inhibitor of Aflatoxin production by Aspergillus parasiticus. Blasticidin A almost completely inhibits Aflatoxin production at 0.5 μM. Blasticidin A is a potent antibiotic produced by Streptomyces, inhibits Aflatoxin production without strong growth inhibition toward Aflatoxin-producing fungi.
    Blasticidin A
  • HY-N29777
    Cabraleahydroxylactone
    Inhibitor
    Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis.
    Cabraleahydroxylactone
  • HY-147940
    TbPTR1 inhibitor 1
    Inhibitor
    TbPTR1 inhibitor 1 (compound 5d) is a potent kinetoplastid pteridine reductase 1 (PTR1) inhibitor with an IC50<0.1 nM for TbPTR1. TbPTR1 inhibitor 1 has inhibitory activity against Trypanosoma brucei (EC50=0.66 μM).
    TbPTR1 inhibitor 1
  • HY-W019773S1
    Albendazole sulfone-d3
    Inhibitor
    Albendazole sulfone-d3 is the deuterium labeled Albendazole sulfone. Albendazole sulfone is a metabolite of Albendazole, and exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes.
    Albendazole sulfone-d<sub>3</sub>
  • HY-B0148R
    Risedronic acid (Standard)
    Inhibitor
    Risedronic acid (Standard) (Risedronate (Standard)) is the analytical standard of Risedronic acid (HY-B0148). This product is intended for research and analytical applications. Risedronic acid (Risedronate) is a bisphosphonate and potent antiresorptive agent. Risedronic acid induces Apoptosis. Risedronic acid inhibits the transfer of farnesyl pyrophosphate groups to parasite proteins. Risedronic acid inhibits osteoclast-mediated bone resorption and alters bone metabolism. Risedronic acid inhibits blood-stage Plasmodium falciparum (IC50 of 20.3 μM).
    Risedronic acid (Standard)
  • HY-136943
    K-41
    Inhibitor
    K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity.
    K-41
  • HY-B1071R
    Lasalocid (Standard)
    Lasalocid (Standard) is the analytical standard of Lasalocid. This product is intended for research and analytical applications. Lasalocid (Lasalocid-A) is an antibacterial and anticoccidial agent that can be used as feed additives. Lasalocid exhibits antitumor activity. Lasalocid is orally active.
    Lasalocid (Standard)
  • HY-118421
    Nullscript
    Inhibitor
    Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid. Scriptaid is a representative HDAC inhibitor. Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC50 value of 2.1 μM.
    Nullscript
  • HY-168208
    Antimalarial agent 45
    Inhibitor
    Antimalarial agent 45 (compound 8I) is a antimalarial agent and shows antiplasmodial activity the IC50 of 0.21 μM. Antimalarial agent 45 can be used for study of malaria.
    Antimalarial agent 45
  • HY-78131S1
    Ibuprofen-13C,d3
    Inhibitor
    Ibuprofen-13C,d3 is the 13C- and deuterium labeled Ibuprofen. Ibuprofen is an anti-inflammatory agent targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.
    Ibuprofen-<sup>13</sup>C,d<sub>3</sub>
  • HY-N2753
    7-Acetoxybonducellpin C
    Inhibitor
    7-Acetoxybonducellpin C, a diterpenoid, is a nature product that could be isolated from the seed kernels of Caesalpinia crista. 7-Acetoxybonducellpin C has antimalarial activity.
    7-Acetoxybonducellpin C

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